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PI: James Brewer, MD, PhD

Time Involved

This is a longitudinal study that will span 18 months with an extension.


Your participation in this research may help us learn how to stop the progression of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in future generations. The goal of this research study is to determine whether the imaging of the brain (through MRI, PET and amyloid imaging scans) can help predict and monitor the onset and progression of AD. In addition to neuroimaging, the study will collect and test blood and cerebral spinal fluid to determine if biomarkers can predict and monitor the disease.


  • Are between 55 and 90 years of age.
  • Are in good general health but have memory problems or concerns
  • Are fluent in English or Spanish- Are willing and able to undergo the test procedures
  • Have a study partner – a friend or relative who can accompany the volunteer to all clinic visits


Helen Vanderswag, RN (858) 822-4800


Click here to watch a video about participation in the study