If you are interested in any of the aforementioned studies or if you are interested in participating in a research study but don't currently see one that suits you, you can now join our research registry to be placed on a list for future studies.
*Call the ADRC 858-822-4800 and ask for Christina Gigliotti, Ph.D. for more information about research participation or being added to our registry.
Stem Cells Derived from Skin Fibroblasts PI: Douglas Galasko, MD Contact: Christina Gigliotti, PhD 858-822-4800 (firstname.lastname@example.org)
Time involved: one time only
Description: The purpose of this study is to study mechanisms of brain aging by deriving neurons from skin biopsies. A small piece of skin is removed from the forearm, the cells are gown in a dish, and induced to become neurons.
Requirements: Age 65 and older; Normal cognition; study partner.
Normal Aging Longitudinal Study
Our investigators are seeking to better understand the transition from normal aging to AD by identifying healthy older adults and those who may be at high risk for developing AD. Studying normal aging enables the researchers to have the reference points necessary to reach valid conclusions about Alzheimer’s disease. We are able to provide testing to Hispanic spanish speaking individuals in English and/or Spanish.
Participants must have a study partner, have stable health status, and must not have any history of major strokes.
Two major benefits are having access to staff members who evaluate your condition and will...
(1) inform you of the results of the evaluation and
(2) make suggestions and referrals for coping with any problems that you may have
Consultation with our social workers is also available as needed
There is no financial cost to participate in our longitudinal research study. The only cost to you is in travel, time, and effort involved in receiving an annual evaluation.
You may withdraw at any time. We would, however like a commitment of a minimum of five years in order to gather the optimal longitudinal data.
Annual visits that last one and a half days. The annual exam consists of three parts: a nursing exam, a neuropsychological assessment, and a neurology exam. In addition, participants will be asked to undergo a volumetric brain MRI scan and a spinal fluid draw (lumbar punture procedure).
We also request that you agree to a brain autopsy. This is critical to our research, since the pathological confirmation is the only definitive diagnosis for the disease. It also provides tissue for critical studies in the pathophysiology of the disease.